Treatment of locally advanced stage 1 to 3 triple negative breast cancer
Breast cancer is the most common female cancer in the US, the second most common cause of cancer death in women, and the main cause of death in women ages 40 to 59.
Important risk factors for breast cancer are age (older), gender (female), reproductive history (less children), hormonal factors (early menses and late menopause), and family history.
Triple-negative breast cancer refers to any breast cancer that does not express the genes for estrogen receptor (ER), progesterone receptor (PR) or Her2/neu.
Triple negative is sometimes used as a surrogate term for basal-like, however more detailed classification is possible providing better guidance for treatment and better estimates for prognosis.
Treatment of Triple Negative Breast Cancer:
Standard treatment is surgery with adjuvant (after surgery) chemotherapy and radiotherapy.
As a variation neoadjuvant (before surgery) chemotherapy is very frequently used for triple negative breast cancers. This allows for a higher rate of breast conserving surgeries and by evaluating the response to the chemotherapy gives important clues about the individual responsiveness of the particular cancer to chemotherapy.
Here, Dr. Tony Talebi discusses the treatment of locally advanced stage 1 to 3 triple negative breast cancer with Dr. Stefan Gluck including breast cancer stage
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Dr. Stephan Gluck is currently a professor of medicine at the University of Miami Sylvester Comprehensive Cancer Center.
Dr. Gluck Credentials:
-Associate Division Chief for Clinical Affairs, Division of Hematology/Oncology
-Clinical Director, Braman Family Breast Cancer Institute
