Home > Patient Educational Videos > Breast Cancer : Triple Negative Breast Cancer - Treatment of Locally Advanced Stage 1 to 3 Disease

Treatment of locally advanced stage 1 to 3 triple negative breast cancer

Breast cancer is the most common female cancer in the US, the second most common cause of cancer death in women, and the main cause of death in women ages 40 to 59.

Important risk factors for breast cancer are age (older), gender (female), reproductive history (less children), hormonal factors (early menses and late menopause), and family history. 

Triple-negative breast cancer refers to any breast cancer that does not express the genes for estrogen receptor (ER), progesterone receptor (PR) or Her2/neu.

Triple negative is sometimes used as a surrogate term for basal-like, however more detailed classification is possible providing better guidance for treatment and better estimates for prognosis.

Treatment of Triple Negative Breast Cancer:

Standard treatment is surgery with adjuvant (after surgery) chemotherapy and radiotherapy.

As a variation neoadjuvant (before surgery) chemotherapy is very frequently used for triple negative breast cancers. This allows for a higher rate of breast conserving surgeries and by evaluating the response to the chemotherapy gives important clues about the individual responsiveness of the particular cancer to chemotherapy.

Here, Dr. Tony Talebi discusses the treatment of locally advanced stage 1 to 3 triple negative breast cancer with Dr. Stefan Gluck including breast cancer stage treatment, advanced breast cancer treatment, symptom of breast cancer, new treatments for breast cancer, stage 1 breast cancer treatment, stage 4 cancer treatment, early symptoms of breast cancer, early symptoms of breast cancer, staging of breast cancer, symptoms for breast cancer, stage iv breast cancer treatment, breast cancer cells, men breast cancer, breast cancer in women, risk factors of breast cancer, radiation for breast cancer, chemotherapy for breast cancer, breast cancer radiation, advanced cancer treatment, what causes breast cancer, articles on breast cancer, facts on breast cancer, stage 3 breast cancer, risk factors for breast cancer, symptoms of cancer, breast cancer survival rates, what cause breast cancer, breast cancer risk factors, stage 3 breast cancer prognosis, survival rate for breast cancer, early stage breast cancer, images of breast cancer, inflammatory breast cancer symptoms, how is breast cancer diagnosed, breast cancer holistic treatment, triple negative breast cancer prognosis, triple negative breast cancer survival, effects of breast cancer, holistic cancer treatment, different types of breast cancer, first signs of breast cancer, stage 4 breast cancer prognosis, definition of breast cancer, statistics of breast cancer.

Dr. Stephan Gluck is currently a professor of medicine at the University of Miami Sylvester Comprehensive Cancer Center.

Dr. Gluck Credentials:

-Associate Division Chief for Clinical Affairs, Division of Hematology/Oncology

-Clinical Director, Braman Family Breast Cancer Institute



University of Toronto
Toronto, Canada


Bone Marrow Transplant and Medical Oncology


Heinrich Heine University
Dusseldorf, Germany

Chief Resident

Internal Medicine


Heinrich Heine University
Dusseldorf, Germany


Internal Medicine


RWTH Aachen
Aachen, Germany


Experimental Pharmacology


Free University of West Berlin
Berlin, Germany


Internal Medicine


Free University of West Berlin
Berlin, Germany

Rotating Internship

Internal Medicine


Ruhr Universitaet
Bochum, Germany


Pre-Clinical Sciences