Home > Patient Educational Videos > Neuroendocrine Tumors - General Concepts : What is a Neuroendocrine Tumor?

What is a Neuroendocrine Tumor:

Neuroendocrine tumors are a heterogeneous group of neoplasms that vary in their appearance, biologic behavior, symptoms, and response to treatment. Several types of neuroendocrine tumors (eg, carcinoid tumors, pancreatic neuroendocrine tumors, medullary thyroid cancers, pheochromocytomas) are characterized by slow growth and frequent secretion of hormones or vasoactive substances. In most cases, these tumors also have typical histologic appearance and are accurately diagnosed with standard pathologic methods (light microscopy and immunohistochemical staining). Other neuroendocrine tumors, typified by small cell carcinoma of the lung, are highly aggressive neoplasms, and are usually advanced when diagnosed.

Well differentiated neuroendocrine tumors originating in the gastrointestinal tract (carcinoid, pancreatic neuroendocrine tumors) are the most common neuroendocrine tumors. However, these are not the most common neuroendocrine tumors presenting with unknown primary site, since most are diagnosed at an early stage and cured by surgical resection. 

Poorly differentiated neuroendocrine tumors are characterized by multiple sites of metastases and rarely produce symptoms related to secretion of bioactive substances. Accurate distinction of well differentiated, indolent tumors from poorly differentiated, aggressive tumors is important, since treatment approaches are different

Here, Dr. Tony Talebi discusses the general concepts of what is a neuroendocrine tumor with Dr. Jonathan Strosberg, an assitant professor of medicine at the Lee Moffitt Comprehensive Cancer Center and a specialist in neuroendocrine tumors.  The discussion includes Neuroendocrine tumor prognosis, what causes Neuroendocrine tumor, signs of Neuroendocrine tumor, Neuroendocrine tumor symptoms, Neuroendocrine tumor, Neuroendocrine tumor stage 4, treatment of Neuroendocrine tumor, Neuroendocrine tumor association, stage four Neuroendocrine tumor, small cell Neuroendocrine tumor, symtoms of Neuroendocrine tumor, causes of Neuroendocrine tumor, Neuroendocrine tumor chemotherapy, what is Neuroendocrine tumor, Neuroendocrine tumors, Neuroendocrine tumor information, Neuroendocrine tumor prevention, stage 4 Neuroendocrine tumor, information about Neuroendocrine tumor, stage iv Neuroendocrine tumor, Neuroendocrine tumor signs, Neuroendocrine tumor symptom, is Neuroendocrine tumor curable, stage 3b Neuroendocrine tumor, lungs cancer symptoms, survival rates for Neuroendocrine tumor, symptoms of Neuroendocrine tumor, Neuroendocrine tumor survivors, Neuroendocrine tumor symptons, Neuroendocrine tumor survival, treatments of Neuroendocrine tumor, symptons of Neuroendocrine tumor, Neuroendocrine tumor statistics, non small cell Neuroendocrine tumor, chemo for Neuroendocrine tumor, Neuroendocrine tumor survival rate, large cell Neuroendocrine tumor, effects of Neuroendocrine tumor, Neuroendocrine tumor screening, Neuroendocrine tumor diagnosis, Neuroendocrine tumor society, Neuroendocrine tumor clinical trials, Neuroendocrine tumor metastasis, survival rate Neuroendocrine tumor, symptom of Neuroendocrine tumor, info on Neuroendocrine tumor, new treatments for Neuroendocrine tumor, how common is Neuroendocrine tumor

Dr. Strosberg credentials:

Faculty Rank:

Assistant Member


Department/Program Affiliations:

  • Experimental Therapeutics  
  • Gastrointestinal Tumor  

Primary Address:

H. Lee Moffitt Cancer Center & 
Research Institute

Education & Training:

  • BA, Harvard University, 1995
  • MD, Cornell University Medical College, 1999
  • Resident, Georgetown University Hospital, 2001 - General Internal Medicine
  • Fellow, H. Lee Moffitt Cancer Center & Research Institute, 2006 - Medical Oncology & Hematology

General Board Certification / SubSpecialty:

  • Internal Medicine / Hematology
  • Internal Medicine / Medical Oncology